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CRISPulator: a discrete simulation tool for pooled genetic screens
BACKGROUND: The rapid adoption of CRISPR technology has enabled biomedical researchers to conduct CRISPR-based genetic screens in a pooled format. The quality of results from such screens is heavily dependent on the selection of optimal screen design parameters, which also affects cost and scalabili...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2017
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5521134/ https://www.ncbi.nlm.nih.gov/pubmed/28732459 http://dx.doi.org/10.1186/s12859-017-1759-9 |