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PARP1 restricts Epstein Barr Virus lytic reactivation by binding the BZLF1 promoter

The Epstein Barr virus (EBV) genome persists in infected host cells as a chromatinized episome and is subject to chromatin-mediated regulation. Binding of the host insulator protein CTCF to the EBV genome has an established role in maintaining viral latency type, and in other herpesviruses, loss of...

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Detalles Bibliográficos
Autores principales: Lupey-Green, Lena N., Moquin, Stephanie A., Martin, Kayla A., McDevitt, Shane M., Hulse, Michael, Caruso, Lisa B., Pomerantz, Richard T., Miranda, JJ L., Tempera, Italo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5521201/
https://www.ncbi.nlm.nih.gov/pubmed/28456021
http://dx.doi.org/10.1016/j.virol.2017.04.006