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PARP1 restricts Epstein Barr Virus lytic reactivation by binding the BZLF1 promoter
The Epstein Barr virus (EBV) genome persists in infected host cells as a chromatinized episome and is subject to chromatin-mediated regulation. Binding of the host insulator protein CTCF to the EBV genome has an established role in maintaining viral latency type, and in other herpesviruses, loss of...
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5521201/ https://www.ncbi.nlm.nih.gov/pubmed/28456021 http://dx.doi.org/10.1016/j.virol.2017.04.006 |