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Association between UGT2B7 gene polymorphisms and fentanyl sensitivity in patients undergoing painful orthognathic surgery

BACKGROUND: Fentanyl is often used instead of morphine for the treatment of pain because it has fewer side effects. The metabolism of morphine by glucuronidation is known to be influenced by polymorphisms of the UGT2B7 gene. Some metabolic products of fentanyl are reportedly metabolized by glucurona...

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Detalles Bibliográficos
Autores principales: Muraoka, Wataru, Nishizawa, Daisuke, Fukuda, Kenichi, Kasai, Shinya, Hasegawa, Junko, Wajima, Koichi, Nakagawa, Taneaki, Ikeda, Kazutaka
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5521342/
https://www.ncbi.nlm.nih.gov/pubmed/28256933
http://dx.doi.org/10.1177/1744806916683182