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Peripheral Inflammation, Apolipoprotein E4, and Amyloid-β Interact to Induce Cognitive and Cerebrovascular Dysfunction

Cerebrovascular dysfunction is rapidly reemerging as a major process of Alzheimer’s disease (AD). It is, therefore, crucial to delineate the roles of AD risk factors in cerebrovascular dysfunction. While apolipoprotein E4 (APOE4), Amyloid-β (Aβ), and peripheral inflammation independently induce cere...

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Detalles Bibliográficos
Autores principales: Marottoli, Felecia M., Katsumata, Yuriko, Koster, Kevin P., Thomas, Riya, Fardo, David W., Tai, Leon M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5521356/
https://www.ncbi.nlm.nih.gov/pubmed/28707482
http://dx.doi.org/10.1177/1759091417719201