Cx47 fine-tunes the handling of serum lipids but is dispensable for lymphatic vascular function

Mutations in the gap junction protein connexin47 (Cx47) are associated with lymphedema. However, the role of Cx47 in lymphatic pathophysiology is unknown. We demonstrate that Cx47 is expressed in lymphatic endothelial cells by whole-mount immunostaining and qPCR. To determine if Cx47 plays a role in...

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Detalles Bibliográficos
Autores principales: Meens, Merlijn J., Kutkut, Issa, Rochemont, Viviane, Dubrot, Juan, Kaladji, Fouad R., Sabine, Amélie, Lyons, Oliver, Hendrikx, Stefanie, Bernier-Latmani, Jeremiah, Kiefer, Friedemann, Smith, Alberto, Hugues, Stéphanie, Petrova, Tatiana V., Kwak, Brenda R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5521787/
https://www.ncbi.nlm.nih.gov/pubmed/28732089
http://dx.doi.org/10.1371/journal.pone.0181476

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5521787/
https://www.ncbi.nlm.nih.gov/pubmed/28732089
http://dx.doi.org/10.1371/journal.pone.0181476

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