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Cx47 fine-tunes the handling of serum lipids but is dispensable for lymphatic vascular function
Mutations in the gap junction protein connexin47 (Cx47) are associated with lymphedema. However, the role of Cx47 in lymphatic pathophysiology is unknown. We demonstrate that Cx47 is expressed in lymphatic endothelial cells by whole-mount immunostaining and qPCR. To determine if Cx47 plays a role in...
Autores principales: | Meens, Merlijn J., Kutkut, Issa, Rochemont, Viviane, Dubrot, Juan, Kaladji, Fouad R., Sabine, Amélie, Lyons, Oliver, Hendrikx, Stefanie, Bernier-Latmani, Jeremiah, Kiefer, Friedemann, Smith, Alberto, Hugues, Stéphanie, Petrova, Tatiana V., Kwak, Brenda R. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5521787/ https://www.ncbi.nlm.nih.gov/pubmed/28732089 http://dx.doi.org/10.1371/journal.pone.0181476 |
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