Understanding Russell’s viper venom factor V activator’s substrate specificity by surface plasmon resonance and in-silico studies

Blood coagulation factor V (FV) is activated either by Factor X or thrombin, cleaving at three different sites viz., Site I (Arg709-Ser710), site II (Arg1018-Thr1019), and site III (Arg1545-Ser1546). Russell’s viper venom factor V activator (RVV-V) is a thrombin-like serine proteinase that activates...

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Detalles Bibliográficos
Autores principales: Yadav, Pradeep K., Antonyraj, Christian B., Basheer Ahamed, Syed Ibrahim, Srinivas, Sistla
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5521794/
https://www.ncbi.nlm.nih.gov/pubmed/28732041
http://dx.doi.org/10.1371/journal.pone.0181216

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5521794/
https://www.ncbi.nlm.nih.gov/pubmed/28732041
http://dx.doi.org/10.1371/journal.pone.0181216

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