A Genome-Wide Association Study Using a Custom Genotyping Array Identifies Variants in GPR158 Associated With Reduced Energy Expenditure in American Indians

Pima Indians living in Arizona have a high prevalence of obesity, and we have previously shown that a relatively lower energy expenditure (EE) predicts weight and fat mass gain in this population. EE is a familial trait (heritability = 0.52); therefore, in the current study, we aimed to identify gen...

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Detalles Bibliográficos
Autores principales: Piaggi, Paolo, Masindova, Ivica, Muller, Yunhua L., Mercader, Josep, Wiessner, Gregory B., Chen, Peng, Kobes, Sayuko, Hsueh, Wen-Chi, Mongalo, Milliejoan, Knowler, William C., Krakoff, Jonathan, Hanson, Robert L., Bogardus, Clifton, Baier, Leslie J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Diabetes Association 2017
Materias:
Genetics/Genomes/Proteomics/Metabolomics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5521859/
https://www.ncbi.nlm.nih.gov/pubmed/28476931
http://dx.doi.org/10.2337/db16-1565

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5521859/
https://www.ncbi.nlm.nih.gov/pubmed/28476931
http://dx.doi.org/10.2337/db16-1565

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