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Hypothalamic Ventromedial Lin28a Enhances Glucose Metabolism in Diet-Induced Obesity
The Lin28a/Let-7 axis has been studied in peripheral tissues for its role in metabolism regulation. However, its central function remains unclear. Here we found that Lin28a is highly expressed in the hypothalamus compared with peripheral tissues. Its expression is positively correlated with positive...
Autores principales: | Kim, Jung Dae, Toda, Chitoku, Ramírez, Cristina M., Fernández-Hernando, Carlos, Diano, Sabrina |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Diabetes Association
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5521863/ https://www.ncbi.nlm.nih.gov/pubmed/28550108 http://dx.doi.org/10.2337/db16-1558 |
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