Frame shift mutations as a novel mechanism for the generation of neutralization resistant mutants of human respiratory syncytial virus.

The genetic characterization of four previously reported mutants of human respiratory syncytial (RS) virus resistant to monoclonal antibody 63G is described. Sequences of the G protein genes were obtained from: (i) mRNA derived cDNA recombinants, (ii) direct mRNA sequencing and (iii) amplified vRNA...

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Detalles Bibliográficos
Autores principales: García-Barreno, B, Portela, A, Delgado, T, López, J A, Melero, J A
Formato: Texto
Lenguaje:English
Publicado: 1990
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC552194/
https://www.ncbi.nlm.nih.gov/pubmed/2249671

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC552194/
https://www.ncbi.nlm.nih.gov/pubmed/2249671

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