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Three-dimensional positioning and structure of chromosomes in a human prophase nucleus

The human genetic material is packaged into 46 chromosomes. The structure of chromosomes is known at the lowest level, where the DNA chain is wrapped around a core of eight histone proteins to form nucleosomes. Around a million of these nucleosomes, each about 11 nm in diameter and 6 nm in thickness...

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Detalles Bibliográficos
Autores principales: Chen, Bo, Yusuf, Mohammed, Hashimoto, Teruo, Estandarte, Ana Katrina, Thompson, George, Robinson, Ian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5521992/
https://www.ncbi.nlm.nih.gov/pubmed/28776025
http://dx.doi.org/10.1126/sciadv.1602231