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Local delivery of HMGB1 in gelatin sponge scaffolds combined with mesenchymal stem cell sheets to accelerate fracture healing

Fracture nonunion and delayed union continue to pose challenges for orthopedic surgeons. In the present study, we combined HMGB1 gelatin sponges with MSC sheets to promote bone healing after surgical treatment of rat tibial fractures. The HMGB1 gelatin sponge scaffolds supported the expansion of mes...

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Detalles Bibliográficos
Autores principales: Xue, Deting, Zhang, Wei, Chen, Erman, Gao, Xiang, Liu, Ling, Ye, Chenyi, Tan, Yanbin, Pan, Zhijun, Li, Hang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5522052/
https://www.ncbi.nlm.nih.gov/pubmed/28431400
http://dx.doi.org/10.18632/oncotarget.16887