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GSPE reduces lead-induced oxidative stress by activating the Nrf2 pathway and suppressing miR153 and GSK-3β in rat kidney

Lead (Pb) is a global environmental health hazard that leads to nephrotoxicity. However, the effective treatment of Pb-induced nephrotoxicity remains elusive. Grape seed procyanidin extract (GSPE) has beneficial properties for multiple biological functions. Therefore, the present study investigated...

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Detalles Bibliográficos
Autores principales: Liu, Biying, Zhang, Haili, Tan, Xiao, Yang, Daqian, Lv, Zhanjun, Jiang, Huijie, Lu, Jingjing, Baiyun, Ruiqi, Zhang, Zhigang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5522062/
https://www.ncbi.nlm.nih.gov/pubmed/28178683
http://dx.doi.org/10.18632/oncotarget.15033