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GALNT6 expression enhances aggressive phenotypes of ovarian cancer cells by regulating EGFR activity

Ovarian cancer is the most lethal of the gynecologic malignancies. N-acetylgalactosaminyltransferase 6 (GALNT6), an enzyme that mediates the initial step of mucin type-O glycosylation, has been reported to regulate mammary carcinogenesis. However, the expression and role of GALNT6 in ovarian cancer...

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Detalles Bibliográficos
Autores principales: Lin, Tzu-Chi, Chen, Syue-Ting, Huang, Min-Chuan, Huang, John, Hsu, Chia-Lang, Juan, Hsueh-Fen, Lin, Ho-Hsiung, Chen, Chi-Hau
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5522090/
https://www.ncbi.nlm.nih.gov/pubmed/28388560
http://dx.doi.org/10.18632/oncotarget.16585