The palmitoylation of the N-terminal extracellular Cys37 mediates the nuclear translocation of VPAC1 contributing to its anti-apoptotic activity

VPAC1 is class B G protein-coupled receptors (GPCR) shared by pituitary adenylate cyclase activating polypeptide (PACAP) and vasoactive intestinal peptide (VIP). The first cysteine (Cys37) in the N-terminal extracellular domain of mature VPAC1 is a free Cys not involved in the formation of conserved...

Descripción completa

Detalles Bibliográficos
Autores principales: Yu, Rongjie, Liu, Hongyu, Peng, Xinhe, Cui, Yue, Song, Suqin, Wang, Like, Zhang, Huahua, Hong, An, Zhou, Tianhong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5522101/
https://www.ncbi.nlm.nih.gov/pubmed/28473666
http://dx.doi.org/10.18632/oncotarget.17449

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5522101/
https://www.ncbi.nlm.nih.gov/pubmed/28473666
http://dx.doi.org/10.18632/oncotarget.17449

Ejemplares similares