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Charge reversible calcium phosphate lipid hybrid nanoparticle for siRNA delivery

Bcl-2 gene is an important target to treat lung cancer. The small interference RNA (siRNA) of Bcl-2 gene (siBcl-2) can specifically silence Bcl-2 gene. However, naked siBcl-2 is difficult to accumulate in the tumor tissue to exert its activity. In this paper, a calcium phosphate lipid hybrid nanopar...

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Detalles Bibliográficos
Autores principales: Cai, Rong-Qiao, Liu, Dao-Zhou, Cui, Han, Cheng, Ying, Liu, Miao, Zhang, Bang-Le, Mei, Qi-Bing, Zhou, Si-Yuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5522105/
https://www.ncbi.nlm.nih.gov/pubmed/28514759
http://dx.doi.org/10.18632/oncotarget.17484