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Charge reversible calcium phosphate lipid hybrid nanoparticle for siRNA delivery
Bcl-2 gene is an important target to treat lung cancer. The small interference RNA (siRNA) of Bcl-2 gene (siBcl-2) can specifically silence Bcl-2 gene. However, naked siBcl-2 is difficult to accumulate in the tumor tissue to exert its activity. In this paper, a calcium phosphate lipid hybrid nanopar...
Autores principales: | Cai, Rong-Qiao, Liu, Dao-Zhou, Cui, Han, Cheng, Ying, Liu, Miao, Zhang, Bang-Le, Mei, Qi-Bing, Zhou, Si-Yuan |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5522105/ https://www.ncbi.nlm.nih.gov/pubmed/28514759 http://dx.doi.org/10.18632/oncotarget.17484 |
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