IL-17RC is critically required to maintain baseline A20 production to repress JNK isoform-dependent tumor-specific proliferation

The IL-17/IL-17R axis has controversial roles in cancer, which may be explained by tumor-specific results. Here, we describe a novel molecular mechanism underlying IL-17RC-controlled tumor-specific proliferation. Triggered by IL-17RC knockdown (KD), B16 melanoma and 4T1 carcinoma cells inversely alt...

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Detalles Bibliográficos
Autores principales: Yan, Chi, Lei, Yang, Lin, Tong-Jun, Hoskin, David W., Ma, Averil, Wang, Jun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5522135/
https://www.ncbi.nlm.nih.gov/pubmed/28562353
http://dx.doi.org/10.18632/oncotarget.17820

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5522135/
https://www.ncbi.nlm.nih.gov/pubmed/28562353
http://dx.doi.org/10.18632/oncotarget.17820

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