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IL-17RC is critically required to maintain baseline A20 production to repress JNK isoform-dependent tumor-specific proliferation

The IL-17/IL-17R axis has controversial roles in cancer, which may be explained by tumor-specific results. Here, we describe a novel molecular mechanism underlying IL-17RC-controlled tumor-specific proliferation. Triggered by IL-17RC knockdown (KD), B16 melanoma and 4T1 carcinoma cells inversely alt...

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Detalles Bibliográficos
Autores principales:	Yan, Chi, Lei, Yang, Lin, Tong-Jun, Hoskin, David W., Ma, Averil, Wang, Jun
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Impact Journals LLC 2017
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5522135/ https://www.ncbi.nlm.nih.gov/pubmed/28562353 http://dx.doi.org/10.18632/oncotarget.17820

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