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Discoidin domain receptor 1 modulates insulin receptor signaling and biological responses in breast cancer cells
The fetal isoform A of the insulin receptor (IR-A) is frequently overexpressed in a variety of malignancies including breast cancer. IR overexpression has a recognized role in cancer progression and resistance to anticancer therapies. In particular, IR-A has a peculiar mitogenic potential and is act...
Autores principales: | , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5522143/ https://www.ncbi.nlm.nih.gov/pubmed/28591735 http://dx.doi.org/10.18632/oncotarget.18020 |