Cargando…

Discoidin domain receptor 1 modulates insulin receptor signaling and biological responses in breast cancer cells

The fetal isoform A of the insulin receptor (IR-A) is frequently overexpressed in a variety of malignancies including breast cancer. IR overexpression has a recognized role in cancer progression and resistance to anticancer therapies. In particular, IR-A has a peculiar mitogenic potential and is act...

Descripción completa

Detalles Bibliográficos
Autores principales: Vella, Veronica, Malaguarnera, Roberta, Nicolosi, Maria Luisa, Palladino, Chiara, Spoleti, Cristina, Massimino, Michele, Vigneri, Paolo, Purrello, Michele, Ragusa, Marco, Morrione, Andrea, Belfiore, Antonino
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5522143/
https://www.ncbi.nlm.nih.gov/pubmed/28591735
http://dx.doi.org/10.18632/oncotarget.18020