Motifs in the amino-terminus of CENP-A are required for its accumulation within the nucleus and at the centromere

Centromere protein A (CENP-A) is a variant of core histone H3 that marks the centromere's location on the chromosome. The mechanisms that target the protein to the nucleus and the centromere have not been defined. In this study, we found that deletion of the first 53 but not the first 29 residu...

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Detalles Bibliográficos
Autores principales: Jing, Ruiqi, Xi, Jiajie, Leng, Ye, Chen, Wen, Wang, Guiying, Jia, Wenwen, Kang, Jiuhong, Zhu, Songcheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5522188/
https://www.ncbi.nlm.nih.gov/pubmed/28489565
http://dx.doi.org/10.18632/oncotarget.17204

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5522188/
https://www.ncbi.nlm.nih.gov/pubmed/28489565
http://dx.doi.org/10.18632/oncotarget.17204

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