Targeted next generation sequencing of mucosal melanomas identifies frequent NF1 and RAS mutations

PURPOSE: Mucosal melanoma represents ~1% of all melanomas, frequently having a poor prognosis due to diagnosis at a late stage of disease. Mucosal melanoma differs from cutaneous melanoma not only in terms of poorer clinical outcome but also on the molecular level having e.g. less BRAF and more freq...

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Detalles Bibliográficos
Autores principales: Cosgarea, Ioana, Ugurel, Selma, Sucker, Antje, Livingstone, Elisabeth, Zimmer, Lisa, Ziemer, Mirjana, Utikal, Jochen, Mohr, Peter, Pfeiffer, Christiane, Pföhler, Claudia, Hillen, Uwe, Horn, Susanne, Schadendorf, Dirk, Griewank, Klaus G., Roesch, Alexander
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5522195/
https://www.ncbi.nlm.nih.gov/pubmed/28380455
http://dx.doi.org/10.18632/oncotarget.16542

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5522195/
https://www.ncbi.nlm.nih.gov/pubmed/28380455
http://dx.doi.org/10.18632/oncotarget.16542

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