An AML1-ETO/miR-29b-1 regulatory circuit modulates phenotypic properties of acute myeloid leukemia cells

Acute myeloid leukemia (AML) is characterized by an aggressive clinical course and frequent cytogenetic abnormalities that include specific chromosomal translocations. The 8;21 chromosomal rearrangement disrupts the key hematopoietic RUNX1 transcription factor, and contributes to leukemia through re...

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Detalles Bibliográficos
Autores principales: Zaidi, Sayyed K., Perez, Andrew W., White, Elizabeth S., Lian, Jane B., Stein, Janet L., Stein, Gary S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Priority Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5522207/
https://www.ncbi.nlm.nih.gov/pubmed/28611288
http://dx.doi.org/10.18632/oncotarget.18127

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5522207/
https://www.ncbi.nlm.nih.gov/pubmed/28611288
http://dx.doi.org/10.18632/oncotarget.18127

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