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An AML1-ETO/miR-29b-1 regulatory circuit modulates phenotypic properties of acute myeloid leukemia cells
Acute myeloid leukemia (AML) is characterized by an aggressive clinical course and frequent cytogenetic abnormalities that include specific chromosomal translocations. The 8;21 chromosomal rearrangement disrupts the key hematopoietic RUNX1 transcription factor, and contributes to leukemia through re...
Autores principales: | Zaidi, Sayyed K., Perez, Andrew W., White, Elizabeth S., Lian, Jane B., Stein, Janet L., Stein, Gary S. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5522207/ https://www.ncbi.nlm.nih.gov/pubmed/28611288 http://dx.doi.org/10.18632/oncotarget.18127 |
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