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Evidence of drug-response heterogeneity rapidly generated from a single cancer cell

One cancer cell line is believed to be composed of numerous clones with different drug sensitivity. We sought to investigate the difference of drug-response pattern in clones from a cell line or from a single cell. We showed that 22 clones derived from 4T1 cells were drastically different from each...

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Detalles Bibliográficos
Autores principales: Wang, Rong, Jin, Chengmeng, Hu, Xun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5522224/
https://www.ncbi.nlm.nih.gov/pubmed/28467802
http://dx.doi.org/10.18632/oncotarget.17064