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Tumor immunotherapy: drug-induced neoantigens (xenogenization) and immune checkpoint inhibitors
More than 40 years ago, we discovered that novel transplantation antigens can be induced in vivo or in vitro by treating murine leukemia with dacarbazine. Years later, this phenomenon that we called “Chemical Xenogenization” (CX) and more recently, “Drug-Induced Xenogenization” (DIX), was reproduced...
Autores principales: | Franzese, Ornella, Torino, Francesco, Fuggetta, Maria Pia, Aquino, Angelo, Roselli, Mario, Bonmassar, Enzo, Giuliani, Anna, D’Atri, Stefania |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5522228/ https://www.ncbi.nlm.nih.gov/pubmed/28404974 http://dx.doi.org/10.18632/oncotarget.16335 |
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