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Telomere erosion in NF1 tumorigenesis

Neurofibromatosis type 1 (NF1; MIM# 162200) is a familial cancer syndrome that affects 1 in 3,500 individuals worldwide and is inherited in an autosomal dominant fashion. Malignant Peripheral Nerve Sheath Tumors (MPNSTs) represent a significant cause of morbidity and mortality in NF1 and currently t...

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Detalles Bibliográficos
Autores principales: Jones, Rhiannon E., Grimstead, Julia W., Sedani, Ashni, Baird, Duncan, Upadhyaya, Meena
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5522233/
https://www.ncbi.nlm.nih.gov/pubmed/28454108
http://dx.doi.org/10.18632/oncotarget.16981