Homoharringtonine targets Smad3 and TGF-β pathway to inhibit the proliferation of acute myeloid leukemia cells

Homoharringtonine (HHT) has long and widely been used in China for the treatment of acute myeloid leukemia (AML), the clinical therapeutic effect is significant but the working mechanism is poorly understood. The purpose of this study is to screen the possible target for HHT with virtual screening a...

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Detalles Bibliográficos
Autores principales: Chen, Jian, Mu, Qitian, Li, Xia, Yin, Xiufeng, Yu, Mengxia, Jin, Jing, Li, Chenying, Zhou, Yile, Zhou, Jiani, Suo, Shanshan, Lu, Demin, Jin, Jie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5522237/
https://www.ncbi.nlm.nih.gov/pubmed/28454099
http://dx.doi.org/10.18632/oncotarget.16956

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5522237/
https://www.ncbi.nlm.nih.gov/pubmed/28454099
http://dx.doi.org/10.18632/oncotarget.16956

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