Curcumin enhances the effects of irinotecan on colorectal cancer cells through the generation of reactive oxygen species and activation of the endoplasmic reticulum stress pathway

Although initially effective against metastatic colorectal cancer (CRC), irinotecan-based chemotherapy leads to resistance and adverse toxicity. Curcumin is well known for its anti-cancer effects in many cancers, including CRC. Here, we describe reactive oxygen species (ROS) generation and endoplasm...

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Detalles Bibliográficos
Autores principales: Huang, Yan-Feng, Zhu, Da-Jian, Chen, Xiao-Wu, Chen, Qi-Kang, Luo, Zhen-Tao, Liu, Chang-Chun, Wang, Guo-Xin, Zhang, Wei-Jie, Liao, Nv-Zhu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5522238/
https://www.ncbi.nlm.nih.gov/pubmed/28402965
http://dx.doi.org/10.18632/oncotarget.16828

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5522238/
https://www.ncbi.nlm.nih.gov/pubmed/28402965
http://dx.doi.org/10.18632/oncotarget.16828

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