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Induction of immunoglobulin transcription factor 2 and resistance to MEK inhibitor in melanoma cells

Primary or acquired resistance to MEK inhibitors has been a barrier to successful treatment with MEK inhibitors in many tumors. In this study, we analyzed genome-wide gene expression profiling data from 6 sensitive and 6 resistant cell lines to identify candidate genes whose expression changes are a...

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Detalles Bibliográficos
Autores principales: Hur, Eun-Hye, Goo, Bon-Kwan, Moon, Juhyun, Choi, Yunsuk, Hwang, Jung Jin, Kim, Choung-Soo, Bae, Kyun Seop, Choi, Jene, Cho, Suk Young, Yang, Sang-Hwa, Seo, Jeongbeob, Lee, Gilnam, Lee, Je-Hwan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5522248/
https://www.ncbi.nlm.nih.gov/pubmed/28574827
http://dx.doi.org/10.18632/oncotarget.17866