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Induction of immunoglobulin transcription factor 2 and resistance to MEK inhibitor in melanoma cells
Primary or acquired resistance to MEK inhibitors has been a barrier to successful treatment with MEK inhibitors in many tumors. In this study, we analyzed genome-wide gene expression profiling data from 6 sensitive and 6 resistant cell lines to identify candidate genes whose expression changes are a...
Autores principales: | , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5522248/ https://www.ncbi.nlm.nih.gov/pubmed/28574827 http://dx.doi.org/10.18632/oncotarget.17866 |