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RMP promotes epithelial-mesenchymal transition through NF-κB/CSN2/Snail pathway in hepatocellular carcinoma

Epithelial-mesenchymal transition (EMT) is a significant risk factor for metastasis in hepatocellular carcinoma (HCC) patients and with poor prognosis. In this study, we demonstrate the key role of RPB5-mediating protein (RMP) in EMT of HCC cells and the mechanism by which RMP promote EMT. RMP incre...

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Detalles Bibliográficos
Autores principales: Zhou, Wei, Wang, Qi, Xu, Yi, Jiang, Jingting, Guo, Jingchun, Yu, Huijun, Wei, Wenxiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5522250/
https://www.ncbi.nlm.nih.gov/pubmed/28423737
http://dx.doi.org/10.18632/oncotarget.16177