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Peretinoin, an acyclic retinoid, suppresses steatohepatitis and tumorigenesis by activating autophagy in mice fed an atherogenic high-fat diet

The pathogenesis of non-alcoholic steatohepatitis (NASH) is still unclear and the prevention of the development of hepatocellular carcinoma (HCC) has not been established. We established an atherogenic and high-fat diet mouse model that develops hepatic steatosis, inflammation, fibrosis, and liver t...

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Detalles Bibliográficos
Autores principales: Okada, Hikari, Takabatake, Riuta, Honda, Masao, Takegoshi, Kai, Yamashita, Taro, Nakamura, Mikiko, Shirasaki, Takayoshi, Sakai, Yoshio, Shimakami, Tetsuro, Nagata, Naoto, Takamura, Toshinari, Tanaka, Takuji, Kaneko, Shuichi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5522259/
https://www.ncbi.nlm.nih.gov/pubmed/28591717
http://dx.doi.org/10.18632/oncotarget.18116