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Phosphodiesterase 3A: a new player in development of interstitial cells of Cajal and a prospective target in gastrointestinal stromal tumors (GIST)

We previously identified phosphodiesterase 3A (PDE3A) as a marker for interstitial cells of Cajal (ICC) in adult mouse gut. However, PDE3A expression and function during gut development and in ICC-derived gastrointestinal stromal tumors (GIST) remained unknown. Here we found that PDE3A was expressed...

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Detalles Bibliográficos
Autores principales: Vandenberghe, Pierre, Hagué, Perrine, Hockman, Steven C., Manganiello, Vincent C., Demetter, Pieter, Erneux, Christophe, Vanderwinden, Jean-Marie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5522287/
https://www.ncbi.nlm.nih.gov/pubmed/28454120
http://dx.doi.org/10.18632/oncotarget.17010