Downregulation of microRNA-199b predicts unfavorable prognosis and emerges as a novel therapeutic target which contributes to PP2A inhibition in metastatic colorectal cancer

The tumor suppressor microRNA-199b (miR-199b) is a negative SET regulator associated with poor outcome in some human cancers. However, its expression levels as well as potential biological and clinical significance in colorectal cancer (CRC) remain completely unexplored. The PP2A inhibitor SET has s...

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Detalles Bibliográficos
Autores principales: Cristóbal, Ion, Caramés, Cristina, Rincón, Raúl, Manso, Rebeca, Madoz-Gúrpide, Juan, Torrejón, Blanca, González-Alonso, Paula, Rojo, Federico, García-Foncillas, Jesús
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5522310/
https://www.ncbi.nlm.nih.gov/pubmed/27517624
http://dx.doi.org/10.18632/oncotarget.11174

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5522310/
https://www.ncbi.nlm.nih.gov/pubmed/27517624
http://dx.doi.org/10.18632/oncotarget.11174

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