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Caveolin-1 scaffolding domain peptides enhance anti-inflammatory effect of heme oxygenase-1 through interrupting its interact with caveolin-1

Caveolin-1(Cav-1) scaffolding domain (CSD) peptides compete with the plasma membrane Cav-1, inhibit the interaction of the proteins and Cav-1, and re-store the functions of Cav-1 binding proteins. Heme oxygenase-1 (HO-1) binds to Cav-1 and its enzymatic activity was inhibited. In this study, we inve...

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Detalles Bibliográficos
Autores principales: Weng, Ping, Zhang, Xiao-Tong, Sheng, Qiong, Tian, Wen-Fang, Chen, Jun-Liang, Yuan, Jia-Jia, Zhang, Ji-Ru, Pang, Qing-Feng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5522314/
https://www.ncbi.nlm.nih.gov/pubmed/28402952
http://dx.doi.org/10.18632/oncotarget.16676