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Human intrahepatic CD69 + CD8+ T cells have a tissue resident memory T cell phenotype with reduced cytolytic capacity
Tissue resident memory T cells (T(RM)) have been identified in various tissues, however human liver T(RM) to date remain unidentified. T(RM) can be recognized by CD69 and/or CD103 expression and may play a role in the pathology of chronic hepatitis B (CHB) and hepatitis C virus infection (CHC). Live...
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5522381/ https://www.ncbi.nlm.nih.gov/pubmed/28733665 http://dx.doi.org/10.1038/s41598-017-06352-3 |