Activation of LXRα improves cardiac remodeling induced by pulmonary artery hypertension in rats

Inflammatory factors regulated by NF-κB play a significant role in PAH and myocardial hypertrophy. LXR activation may inhibit myocardial hypertrophy via suppressing inflammatory pathways; it is unknown whether LXR is also involved in PAH-induced myocardial hypertrophy or remodeling. To further explo...

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Detalles Bibliográficos
Autores principales: Gong, Yibo, Yang, Yifeng, Wu, Qin, Gao, Ge, Liu, Yin, Xiong, Yaoyao, Huang, Can, Wu, Sijie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5522383/
https://www.ncbi.nlm.nih.gov/pubmed/28733583
http://dx.doi.org/10.1038/s41598-017-04640-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5522383/
https://www.ncbi.nlm.nih.gov/pubmed/28733583
http://dx.doi.org/10.1038/s41598-017-04640-6

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