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CID fragmentation, H/D exchange and supermetallization of Barnase-Barstar complex

The barnase-barstar complex is one of the most stable protein-protein complexes and has a very wide range of possible applications. Here we report the use of top-down mass spectrometry for the investigation of the structure of this complex, its ionization via ESI, isolation and fragmentation. It was...

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Detalles Bibliográficos
Autores principales: Kostyukevich, Yury, Shulga, Aleksej A., Kononikhin, Alexey, Popov, Igor, Nikolaev, Eugene, Deyev, Sergey
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5522418/
https://www.ncbi.nlm.nih.gov/pubmed/28733680
http://dx.doi.org/10.1038/s41598-017-06507-2