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Role of SCCmec type in resistance to the synergistic activity of oxacillin and cefoxitin in MRSA

β-lactam antibiotics target penicillin-binding proteins (PBPs) preventing peptidoglycan synthesis and this inhibition is circumvented in methicillin resistant Staphylococcus aureus (MRSA) strains through the expression of an additional PBP, named PBP2A. This enzyme is encoded by the mecA gene locate...

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Detalles Bibliográficos
Autores principales: Reichmann, Nathalie T., Pinho, Mariana G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5522475/
https://www.ncbi.nlm.nih.gov/pubmed/28733674
http://dx.doi.org/10.1038/s41598-017-06329-2