PI3K p85α Subunit-deficient Macrophages Protect Mice from Acute Colitis due to the Enhancement of IL-10 Production

We investigated the role of the PI3K p85α subunit in the development of acute colitis with a focus on intestinal macrophages. Experimental acute colitis was induced using 3% dextran sulfate sodium (DSS) in drinking water for 7 days. The severity of DSS-induced acute colitis was significantly attenua...

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Detalles Bibliográficos
Autores principales: Hayashi, Shusaku, Hamada, Takayuki, Zinsou, Donald G. A., Oshiro, Momoe, Itoi, Kana, Yamamoto, Takeshi, Kadowaki, Makoto
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5522489/
https://www.ncbi.nlm.nih.gov/pubmed/28733636
http://dx.doi.org/10.1038/s41598-017-06464-w

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5522489/
https://www.ncbi.nlm.nih.gov/pubmed/28733636
http://dx.doi.org/10.1038/s41598-017-06464-w

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