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Nanoscale Investigation of Generation 1 PAMAM Dendrimers Interaction with a Protein Nanopore

Herein, we describe at uni-molecular level the interactions between poly(amidoamine) (PAMAM) dendrimers of generation 1 and the α-hemolysin protein nanopore, at acidic and neutral pH, and ionic strengths of 0.5 M and 1 M KCl, via single-molecule electrical recordings. The results indicate that kinet...

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Detalles Bibliográficos
Autores principales: Asandei, Alina, Ciuca, Andrei, Apetrei, Aurelia, Schiopu, Irina, Mereuta, Loredana, Seo, Chang Ho, Park, Yoonkyung, Luchian, Tudor
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5522495/
https://www.ncbi.nlm.nih.gov/pubmed/28733599
http://dx.doi.org/10.1038/s41598-017-06435-1