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Selective and interactive effects of D(2) receptor antagonism and positive allosteric mGluR4 modulation on waiting impulsivity

BACKGROUND: Metabotropic glutamate receptor 4 (mGluR4) and dopamine D(2) receptors are specifically expressed within the indirect pathway neurons of the striato-pallidal-subthalamic pathway. This unique expression profile suggests that mGluR4 and D(2) receptors may play a cooperative role in the reg...

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Detalles Bibliográficos
Autores principales: Isherwood, Sarah N., Robbins, Trevor W., Nicholson, Janet R., Dalley, Jeffrey W., Pekcec, Anton
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Pergamon Press 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5522528/
https://www.ncbi.nlm.nih.gov/pubmed/28487067
http://dx.doi.org/10.1016/j.neuropharm.2017.05.006