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Increased brain expression of GPNMB is associated with genome wide significant risk for Parkinson’s disease on chromosome 7p15.3

Genome wide association studies (GWAS) for Parkinson’s disease (PD) have previously revealed a significant association with a locus on chromosome 7p15.3, initially designated as the glycoprotein non-metastatic melanoma protein B (GPNMB) locus. In this study, the functional consequences of this assoc...

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Detalles Bibliográficos
Autores principales: Murthy, Megha N., Blauwendraat, Cornelis, Guelfi, Sebastian, Hardy, John, Lewis, Patrick A., Trabzuni, Daniah
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5522530/
https://www.ncbi.nlm.nih.gov/pubmed/28391543
http://dx.doi.org/10.1007/s10048-017-0514-8