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Increased brain expression of GPNMB is associated with genome wide significant risk for Parkinson’s disease on chromosome 7p15.3
Genome wide association studies (GWAS) for Parkinson’s disease (PD) have previously revealed a significant association with a locus on chromosome 7p15.3, initially designated as the glycoprotein non-metastatic melanoma protein B (GPNMB) locus. In this study, the functional consequences of this assoc...
Autores principales: | Murthy, Megha N., Blauwendraat, Cornelis, Guelfi, Sebastian, Hardy, John, Lewis, Patrick A., Trabzuni, Daniah |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer Berlin Heidelberg
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5522530/ https://www.ncbi.nlm.nih.gov/pubmed/28391543 http://dx.doi.org/10.1007/s10048-017-0514-8 |
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