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Agonist-induced activation of human FFA1 receptor signals to extracellular signal-regulated kinase 1 and 2 through Gq- and Gi-coupled signaling cascades

BACKGROUND: FFA1 is abundantly expressed in the liver, skeletal muscle, monocytes and nervous system, but is particularly abundant in pancreatic β cells. It is widely believed that FFA1 exerts its regulatory roles in a variety of physiological and pathological functions. In response to oleic acid, F...

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Detalles Bibliográficos
Autores principales: Qian, Jing, Gu, Yuyang, Wu, Chun, Yu, Feng, Chen, Yuqi, Zhu, Jingmei, Yao, Xingyi, Bei, Chen, Zhu, Qingqing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5522598/
https://www.ncbi.nlm.nih.gov/pubmed/28747926
http://dx.doi.org/10.1186/s11658-017-0043-3