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Partner-Drug Resistance and Population Substructuring of Artemisinin-Resistant Plasmodium falciparum in Cambodia

Plasmodium falciparum in western Cambodia has developed resistance to artemisinin and its partner drugs, causing frequent treatment failure. Understanding this evolution can inform the deployment of new therapies. We investigated the genetic architecture of 78 falciparum isolates using whole-genome...

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Detalles Bibliográficos
Autores principales: Parobek, Christian M., Parr, Jonathan B., Brazeau, Nicholas F., Lon, Chanthap, Chaorattanakawee, Suwanna, Gosi, Panita, Barnett, Eric J., Norris, Lauren D., Meshnick, Steven R., Spring, Michele D., Lanteri, Charlotte A., Bailey, Jeffrey A., Saunders, David L., Lin, Jessica T., Juliano, Jonathan J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5522704/
https://www.ncbi.nlm.nih.gov/pubmed/28854635
http://dx.doi.org/10.1093/gbe/evx126