Cargando…

Partner-Drug Resistance and Population Substructuring of Artemisinin-Resistant Plasmodium falciparum in Cambodia

Plasmodium falciparum in western Cambodia has developed resistance to artemisinin and its partner drugs, causing frequent treatment failure. Understanding this evolution can inform the deployment of new therapies. We investigated the genetic architecture of 78 falciparum isolates using whole-genome...

Descripción completa

Detalles Bibliográficos
Autores principales:	Parobek, Christian M., Parr, Jonathan B., Brazeau, Nicholas F., Lon, Chanthap, Chaorattanakawee, Suwanna, Gosi, Panita, Barnett, Eric J., Norris, Lauren D., Meshnick, Steven R., Spring, Michele D., Lanteri, Charlotte A., Bailey, Jeffrey A., Saunders, David L., Lin, Jessica T., Juliano, Jonathan J.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2017
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5522704/ https://www.ncbi.nlm.nih.gov/pubmed/28854635 http://dx.doi.org/10.1093/gbe/evx126

Ejemplares similares

Attenuation of Plasmodium falciparum in vitro drug resistance phenotype following culture adaptation compared to fresh clinical isolates in Cambodia
por: Chaorattanakawee, Suwanna, et al.
Publicado: (2015)

Efficacy of Two versus Three-Day Regimens of Dihydroartemisinin-Piperaquine for Uncomplicated Malaria in Military Personnel in Northern Cambodia: An Open-Label Randomized Trial
por: Lon, Chanthap, et al.
Publicado: (2014)

Single dose primaquine to reduce gametocyte carriage and Plasmodium falciparum transmission in Cambodia: An open-label randomized trial
por: Lin, Jessica T., et al.
Publicado: (2017)

Measuring ex vivo drug susceptibility in Plasmodium vivax isolates from Cambodia
por: Chaorattanakawee, Suwanna, et al.
Publicado: (2017)

Ex vivo piperaquine resistance developed rapidly in Plasmodium falciparum isolates in northern Cambodia compared to Thailand
por: Chaorattanakawee, Suwanna, et al.
Publicado: (2016)

Direct comparison of the histidine-rich protein-2 enzyme-linked immunosorbent assay (HRP-2 ELISA) and malaria SYBR green I fluorescence (MSF) drug sensitivity tests in Plasmodium falciparum reference clones and fresh ex vivo field isolates from Cambodia
por: Chaorattanakawee, Suwanna, et al.
Publicado: (2013)

Evaluation of parasite subpopulations and genetic diversity of the msp1, msp2 and glurp genes during and following artesunate monotherapy treatment of Plasmodium falciparum malaria in Western Cambodia
por: Gosi, Panita, et al.
Publicado: (2013)

Artesunate Dose Escalation for the Treatment of Uncomplicated Malaria in a Region of Reported Artemisinin Resistance: A Randomized Clinical Trial
por: Bethell, Delia, et al.
Publicado: (2011)

Antibody profiles to plasmodium merozoite surface protein-1 in Cambodian adults during an active surveillance cohort with nested treatment study
por: Spring, Michele D., et al.
Publicado: (2016)

Cluster-randomized trial of monthly malaria prophylaxis versus focused screening and treatment: a study protocol to define malaria elimination strategies in Cambodia
por: Manning, Jessica, et al.
Publicado: (2018)

Multiple populations of artemisinin-resistant Plasmodium falciparum in Cambodia
por: Miotto, Olivo, et al.
Publicado: (2013)

Perspective: Artemisinin-Resistant Malaria and the Wolf
por: Meshnick, Steve
Publicado: (2012)

Multidrug-Resistant Shigella Infections in Patients with Diarrhea, Cambodia, 2014–2015
por: Poramathikul, Kamonporn, et al.
Publicado: (2016)

The last man standing is the most resistant: eliminating artemisinin-resistant malaria in Cambodia
por: Maude, Richard J, et al.
Publicado: (2009)

Plasmodium falciparum phenotypic and genotypic resistance profile during the emergence of Piperaquine resistance in Northeastern Thailand
por: Boonyalai, Nonlawat, et al.
Publicado: (2021)

Piperaquine resistant Cambodian Plasmodium falciparum clinical isolates: in vitro genotypic and phenotypic characterization
por: Boonyalai, Nonlawat, et al.
Publicado: (2020)

Functional analysis of Plasmodium falciparum subpopulations associated with artemisinin resistance in Cambodia
por: Dwivedi, Ankit, et al.
Publicado: (2017)

Antimicrobial resistant Helicobacter fennelliae isolated from non-diarrheal child stool sample in Battambang, Cambodia
por: Ruksasiri, Supaporn, et al.
Publicado: (2018)

Ex vivo drug sensitivity profiles of Plasmodium falciparum field isolates from Cambodia and Thailand, 2005 to 2010, determined by a histidine-rich protein-2 assay
por: Tyner, Stuart D, et al.
Publicado: (2012)

Plasmodium falciparum resistant to artemisinin and diagnostics have emerged in Ethiopia
por: Fola, Abebe A., et al.
Publicado: (2023)

Artemisinin resistance without pfkelch13 mutations in Plasmodium falciparum isolates from Cambodia
por: Mukherjee, Angana, et al.
Publicado: (2017)

Prevalence and characterization of piperaquine, mefloquine and artemisinin derivatives triple-resistant Plasmodium falciparum in Cambodia
por: Mairet-Khedim, Mélissa, et al.
Publicado: (2022)

The Cambodia Research Consortium: expediting research for malaria elimination with the emergency response to artemisinin resistance framework
por: Canavati, Sara E., et al.
Publicado: (2016)

Evaluation of the CareStart™ glucose-6-phosphate dehydrogenase (G6PD) rapid diagnostic test in the field settings and assessment of perceived risk from primaquine at the community level in Cambodia
por: Wojnarski, Bertha, et al.
Publicado: (2020)

Plasmodium falciparum sulfadoxine resistance is geographically and genetically clustered within the DR Congo
por: Taylor, Steve M., et al.
Publicado: (2013)

Optimising Strategies for Plasmodium falciparum Malaria Elimination in Cambodia: Primaquine, Mass Drug Administration and Artemisinin Resistance
por: Maude, Richard J., et al.
Publicado: (2012)

Reducing the spread of artemisinin resistant malaria through community-level directly observed therapy in Western of Cambodia
por: Say, Chy, et al.
Publicado: (2012)

Fitness Loss under Amino Acid Starvation in Artemisinin-Resistant Plasmodium falciparum Isolates from Cambodia
por: Bunditvorapoom, Duangkamon, et al.
Publicado: (2018)

Molecular Surveillance for Multidrug-Resistant Plasmodium falciparum, Cambodia
por: Shah, Naman K., et al.
Publicado: (2008)

Severe malaria in Battambang Referral Hospital, an area of multidrug resistance in Western-Cambodia: a retrospective analysis of cases from 2006–2009
por: Lon, Chanthap, et al.
Publicado: (2013)

Use of Oropharyngeal Washes to Diagnose and Genotype Pneumocystis jirovecii
por: Juliano, Jonathan J., et al.
Publicado: (2015)

Optimizing the HRP-2 in vitro malaria drug susceptibility assay using a reference clone to improve comparisons of Plasmodium falciparum field isolates
por: Rutvisuttinunt, Wiriya, et al.
Publicado: (2012)

Detecting geospatial patterns of Plasmodium falciparum parasite migration in Cambodia using optimized estimated effective migration surfaces
por: Li, Yao, et al.
Publicado: (2020)

Access to artemisinin combination therapy for malaria in remote areas of Cambodia
por: Yeung, Shunmay, et al.
Publicado: (2008)

Genetic diversity among Plasmodium vivax isolates along the Thai–Myanmar border of Thailand
por: Maneerattanasak, Sarunya, et al.
Publicado: (2016)

Village malaria worker performance key to the elimination of artemisinin-resistant malaria: a Western Cambodia health system assessment
por: Canavati, Sara E., et al.
Publicado: (2016)

Streamlined, PCR-based testing for pfhrp2- and pfhrp3-negative Plasmodium falciparum
por: Parr, Jonathan B., et al.
Publicado: (2018)

Plasmodium prevalence and artemisinin-resistant falciparum malaria in Preah Vihear Province, Cambodia: a cross-sectional population-based study
por: Bosman, Philippe, et al.
Publicado: (2014)

National dengue surveillance, Cambodia 2002–2020
por: Yek, Christina, et al.
Publicado: (2023)

The changing landscape of Plasmodium falciparum drug resistance in the Democratic Republic of Congo
por: Deutsch-Feldman, Molly, et al.
Publicado: (2019)

Cannot write session to /tmp/vufind_sessions/sess_5rofi3h566q4qgtg7vaamdcgpo