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Population Pharmacokinetic Characteristics of Amikacin in Suspected Cases of Neonatal Sepsis in a Low-Resource African Setting: A Prospective Nonrandomized Single-Site Study

BACKGROUND: Amikacin exhibits marked pharmacokinetic (PK) variability and is commonly used in combination with other drugs in the treatment of neonatal sepsis. There is a paucity of amikacin PK information in neonates from low-resource settings. OBJECTIVES: To determine the PK parameters of amikacin...

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Detalles Bibliográficos
Autores principales: Amponsah, Seth K., Adjei, George O., Enweronu-Laryea, Christabel, Bugyei, Kwasi A., Hadji-Popovski, Kosta, Kurtzhals, Jorgen A.L., Kristensen, Kim
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5522970/
https://www.ncbi.nlm.nih.gov/pubmed/28761582
http://dx.doi.org/10.1016/j.curtheres.2017.01.001