The immunosuppressive cytokine interleukin-4 increases the clonogenic potential of prostate stem-like cells by activation of STAT6 signalling

Interleukin-4 plays a critical role in the regulation of immune responses and has been detected at high levels in the tumour microenvironment of cancer patients, where concentrations correlate with the grade of malignancy. In prostate cancer, interleukin-4 has been associated with activation of the...

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Detalles Bibliográficos
Autores principales: Nappo, G, Handle, F, Santer, F R, McNeill, R V, Seed, R I, Collins, A T, Morrone, G, Culig, Z, Maitland, N J, Erb, H H H
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5523058/
https://www.ncbi.nlm.nih.gov/pubmed/28553931
http://dx.doi.org/10.1038/oncsis.2017.23

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5523058/
https://www.ncbi.nlm.nih.gov/pubmed/28553931
http://dx.doi.org/10.1038/oncsis.2017.23

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