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Epigenetic pathway inhibitors represent potential drugs for treating pancreatic and bronchial neuroendocrine tumors

Cancer is associated with alterations in epigenetic mechanisms such as histone modifications and methylation of DNA, and inhibitors targeting epigenetic mechanisms represent a novel class of anti-cancer drugs. Neuroendocrine tumors (NETs) of the pancreas (PNETs) and bronchus (BNETs), which may have...

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Detalles Bibliográficos
Autores principales: Lines, K E, Stevenson, M, Filippakopoulos, P, Müller, S, Lockstone, H E, Wright, B, Grozinsky-Glasberg, S, Grossman, A B, Knapp, S, Buck, D, Bountra, C, Thakker, R V
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5523063/
https://www.ncbi.nlm.nih.gov/pubmed/28504695
http://dx.doi.org/10.1038/oncsis.2017.30